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Brent W Meier Selected Research

Butylated Hydroxytoluene (BHT)

8/2008Carbonyl reductase inactivation may contribute to mouse lung tumor promotion by electrophilic metabolites of butylated hydroxytoluene: protein alkylation in vivo and in vitro.
2/2007Mechanistic basis for inflammation and tumor promotion in lungs of 2,6-di-tert-butyl-4-methylphenol-treated mice: electrophilic metabolites alkylate and inactivate antioxidant enzymes.
10/2005Immunochemical and proteomic analysis of covalent adducts formed by quinone methide tumor promoters in mouse lung epithelial cell lines.
12/2004Inhibition of glutathione S-transferase P1-1 in mouse lung epithelial cells by the tumor promoter 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone (BHT-quinone methide): protein adducts investigated by electrospray mass spectrometry.

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Brent W Meier Research Topics

Disease

4Neoplasms (Cancer)
08/2008 - 12/2004
3Carcinogenesis
08/2008 - 10/2005
1Pneumonia (Pneumonitis)
08/2008
1Inflammation (Inflammations)
02/2007

Drug/Important Bio-Agent (IBA)

4Proteins (Proteins, Gene)FDA Link
08/2008 - 12/2004
4Butylated Hydroxytoluene (BHT)IBA
08/2008 - 12/2004
3AntioxidantsIBA
08/2008 - 10/2005
2EnzymesIBA
08/2008 - 02/2007
2quinone (benzoquinone)IBA
02/2007 - 12/2004
22,6- di- tert- butyl- 4- methylene- 2,5- cyclohexadienoneIBA
10/2005 - 12/2004
1Food Additives (Food Additive)IBA
08/2008
1Alcohol OxidoreductasesIBA
08/2008
1Reactive Oxygen Species (Oxygen Radicals)IBA
02/2007
1CarcinogensIBA
02/2007
1MethylcholanthreneIBA
02/2007
1BHTOH-QMIBA
10/2005
1quinone methideIBA
10/2005
1Glutathione Transferase (Glutathione S-Transferase)IBA
12/2004
1Oxidants (Oxidizing Agents)IBA
12/2004
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
12/2004
1Phosphotransferases (Kinase)IBA
12/2004

Therapy/Procedure

2Injections
08/2008 - 02/2007